Posts Tagged ‘dermatitis’
July 5th, 2020 by Dr. Hannah Sivak
Filaggrin (filament aggregating protein) plays an essential role in the organization of keratin filaments and the development of the cornified layer (stratum cornueum) of the skin, which is an essential part of the skin barrier to epidermal water loss and to the entry of microbes and noxious substances. (There are some strange aspects to filaggrin, which point to influence beyond the skin. For example, filaggrin mutations are associated with asthma.) Figure: skin layers Dermatitis, a.k.a. eczema is the almost normal state of the skin in which the skin feels tight, itchy, even painful at times. You will see swelling, and the lesions may eventually lead to scarring. Is filaggrin involved…