Soothing Post Radiation Cream

The objectives of this cream are soothing, stopping oxidant chain reactions started by the treatment, and healing,

This very emollient and soothing cream contains melatonin, sea kelp bioferment, vitamin B12, ceramides, Boswellia serrata extract, rosehip oil, tamanu (foraha) oil, pomegranate oil, the best natural antioxidants (Alpha-D-Tocopherol, Lycopene, Tocotrienols, Astaxanthin, Lutein, beta carotene, Alpha Lipoic Acid) and bisabolol. It has been formulated to alleviate the effects of radiation treatment and speed up healing.

Why antioxidants? Once cancer cells have been killed by the treatment, the emphasis should be put on recovery and skin healing. Stopping oxidation chain reactions started by radiation and the overall stress are part of the process.

Melatonin – Melatonin is present naturally in our bodies, secreted by the pineal gland in response to sunlight and overcoming both environmental and endogenous stressors to maintain skin integrity. Topical application of melatonin benefits the skin in many ways, decreasing the damage of radiotherapy on the skin and improving its texture.

Boswellia Serrata Extract – Indian frankincense (Boswellia Serrata) is a tree that grows in the dry, mountainous regions of India. Our extract of Indian frankincense is standarized for the active triterpenoids, called boswellic acids. Boswellia has great properties that makes it an ideal active for skin care, it contains elastase (protease) and hyaluronidase inhibitors, so it is a life preserver for the dermal matrix. It is also an inhibitor of 5-lipoxygenase, the reason why this extract has been used since Biblical times to alleviate arthritis.

Rhodiola Rosea Extract (Roseroot, Golden Root, or Arctic Root) – This extract is used to help with stress, and benefits the skin through several chemicals including rosavin, sitosterol, gallic acid and salidroside.

Ceramides – The stratum corneum, an epidermis layer that limits water loss, consists of flattened cells, the corneocytes, imbedded in a lipid mixture consisting mainly of a lamellar structure of ceramides, cholesterol, and fatty acids. Insufficient synthesis or loss of skin lipids results in an increased water loss and increased penetration of harmful compounds from the environment, causing skin dryness and skin sensitivity. The synthetic ceramides in our cream will enhance skin moisturization and skin protection, helping to repair damaged and dry skin.

Tamanu Oil (also called foraha or doomba oil) is pressed from nuts of the Calophyllum tacamahaca (or ati) or Calophyllum inophyllum tree. The oil originates in Polynesia where it continues to play an important cultural role. Composition varies with environmental conditions but, in general, there is a majority of unsaturated fatty acids; also present are phytosterols, mainly stigmasterol and beta-sitosterol plus tocopherols and tocotrienols (vitamin E).

Vitamin B12 – Cobalamin plays a crucial role in the maintenance of homocysteine and methylmalonyl-CoA homeostasis and is required for DNA synthesis. Deficiency of this vitamin is relatively common, a leads to skin or mucous membranes problems

Bisabolol – This natural chemical is an unsaturated monocyclic sesquiterpene alcohol, partly responsible for the anti-inflammatory effect of chamomile essential oil. Bisabolol is well absorbed and also facilitates the absorption of other ingredients. When applied to skin that has been damaged by burns, bisabolol increased skin hydration, surface lipids, skin elasticity and decreased TEWL (trans-epidermal water loss, i.e. increased the integrity of the skin barrier). The anti-inflammatory effect of bisabolol is comparable to corticosteroid compounds, with the clear advantage that it lacks the side effects that makes the use of corticosteroids like hydrocortisone a last resort.

Fucoidans, extracted and purified from brown algae (Phaeophyta), are sulfated polysaccharides that increase the density of collagen bundles in the skin, decrease activity of proteases (enzymes that break down dermal proteins), increase scavenging of free radicals, and increase cell proliferation. In addition to assisting in collagen synthesis, fucoidan inhibits the replication of many viruses.

Rosehip Seed Oil – This organic, cold pressed oil is made fresh from the seeds of the wild rose (Rosa affinis rubiginosa) that grows in Chile. What is so special about this oil? Rose hip oil is a concentrated solution of linoleic and linolenic acid, two essential fatty acids that are found in the structural lipids of the cell but humans cannot make them. It also contains tocopherols and carotenoids (responsible for the lovely pink/orange color of the oil). In clinical studies with humans, rose hip oil was effective in aiding tissue regeneration in surgical wounds. It is used in repair of burned skin.

Pomegranate Oil – The Latin name of the plant is Punica granatum, granatum for grained apple, Punica because the tree was introduced to Rome from Cartaghe (remember the Punic wars?). Anti-cancer properties of pomegranate seed oil may be derived from the high concentration of conjugated linolenic acids, fatty acids that contain double bonds alternating with single bonds in between. Pomegranate seed oil contains more than 70% cis9, trans11,cis13-18:3 fatty acid. This kind of fatty acid composition is very rare. Pomegranate seed oil is a chemopreventive for skin cancer and, very important, it has shown significant inhibition of proliferation of metastatic breast cancer cells, both estradiol-dependent and estradiol independent. Pomegranate seed oil has been shown to cause breast cancer cells to self-destruct.

Candlenut oil or kuku’i nut oil is extracted from the nut of Aleurites moluccanus. The oil contains unsaturated fatty acids, including oleic, linoleic acid and linolenic acids. Provides emolliency and nutrients essential to skin healing.

Antioxidant Booster – Skin Actives’ concentrated solution of oil soluble antioxidants including various forms of Vitamin E, astaxanthin, alpha lipoic acid and beta-carotene in pomegranate seed oil.

-Dr. Hannah Sivak

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