The answer to the question: not really. What matters is the ingredient list and the formulator may have to change the consistency of the product to  make sure that the actives are dissolved completely. From my book Types of skin care products Cream: an emulsion of oil and water in approximately equal proportions that penetrates well the outer layer of skin. Both oil soluble and water soluble actives can be used. Creams have a higher viscosity (thickness) than lotions. Lotion: a low viscosity topical preparation. Gel: a jelly-like material that can have properties ranging from soft and weak to hard and tough. By weight, gels are mostly liquid, yet they … Continue reading A serum or a cream? Is it important?